in Blood Culture Contamination with the Diversion Method (Clean Collect®)
The effect of the diversion method on blood culture contamination rates
has been studied through two phases of clinical trials. In the first
phase, 248 blood cultures from healthy volunteers demonstrated an 84%
reduction in contamination using an 8.0 mL initial sample. This
study was performed at the Southern Arizona VA Healthcare System under
Dr. Ron Schifman, MD.
the second phase, data from 7,876 hospital patients demonstrated a 42%
reduction with use of smaller initial sample volumes of 0.5 - 1.0 mLs
and a 50% reduction with 2.0 mLs. This study was performed at the
Northwest Medical Center under Dr. Richard Patton, MD. The results were
published in the December 2010 Journal of Clinical Microbiology.
the abstract of this study click
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The effective range of diversion is 1.0 - 8.0 mLs of initial blood flow.
The optimal range to minimize waste and maximize reduction is 4.0 - 6.0